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预测和患病率1001年阻塞性睡眠呼吸暂停和打鼾的中年男人。
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  1. Stradling J R,
  2. J H克罗斯比
  1. 奥斯勒的胸口,丘吉尔医院,牛津。

    文摘

    一千零一名男性,35 - 65岁,从一组的年龄性别注册确认惯例。在四年内900人访问了在家里,询问症状可能与睡眠呼吸暂停和打鼾。身高、体重、颈围、休息动脉氧饱和度(SaO2)和肺量测定的值也被确定。整夜血氧定量法是进行跟踪分析国内外的蘸SaO2数超过4%。超过5 SaO2下降4%或更多的睡眠实验室多导睡眠图每小时被邀请。百分之十七的人承认“经常打鼾。”Multiple linear regression techniques identified and ranked neck circumference (r2 = 7.2%), cigarette consumption (r2 = 3.4%), and nasal stuffiness (r2 = 2%) as the only significant independent predictors of snoring. Together these account for at least a sixfold variation in the likelihood of being an "often" snorer. Forty six subjects (5%) had greater than 4% SaO2 dip rates of over five an hour and 31 of these had full sleep studies. Three subjects had clinically obvious and severe symptomatic obstructive sleep apnoea, giving a prevalence of three per 1001 men (0.3%; 95% confidence interval 0.07-0.9%). Eighteen men had obstructive sleep apnoea only when supine and in 10 the cause of the SaO2 dipping on the original home tracing was not elucidated. The greater than 4% SaO2 dip rates correlated with the history of snoring. Multiple linear regression techniques identified and ranked neck circumference (r2 = 7.9%), alcohol consumption (r2 = 3.7%), age (r2 = 1%) and obesity (r2 = 1%) as the only significant independent predictors of the rate of overnight hypoxic dipping. This study shows that snoring in this randomly selected population correlates best with neck size, smoking, and nasal stuffiness. Obstructive sleep apnoea, defined by nocturnal hypoxaemia, correlates best with neck size and alcohol, and less so with age and general obesity.

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