TY -的T1 breathhold在呼气流量峰值的影响在正常和哮喘儿童JF -欧洲呼吸杂志》乔和J SP - 1363 LP - 1367欧元六世- 9 - 7盟松本,我非盟-沃克,年代盟——狡猾,PD Y1 - 1996/07/01 UR - //www.qdcxjkg.com/content/9/7/1363.abstract N2 -我们曾表现出最大呼气流量(PEF)减少10%的健康成人后breathhold在肺活量(TLC)。今年秋天归因于耗散气道壁粘弹性,增加气道壁合规(地)。调查这一现象在儿童和确定breathhold的影响会更大比正常儿童哮喘病患者,15名哮喘患者和14岁正常儿童(年龄在10 - 15岁)执行最大后到期(MFE)有或没有一个5 s breathhold TLC。整个研究重复吸入后舒喘灵(800毫克)放松气管平滑肌(并增加地)。Breathhold在PEF TLC导致明显降低在哮喘患者(组平均下降5.8%;p < 0.01) and normal children (group mean fall 10.3%; p < 0.05). Salbutamol diminished this fall, becoming nonsignificant in the normal children. Similar patterns were also seen in forced expiratory volume in one second (FEV1) and in maximal expiratory flow at 50% vital capacity (V'50). These data are consistent with the proposal that breathhold at total lung capacity dissipated viscoelastic energy (increasing airway compliance) and decreased maximal expiratory flows both in normal and asthmatic children. They also demonstrate the need to standardize the forced vital capacity manoeuvre to decrease the variability in the flows recorded during the subsequent forced expiration. ER -