Ty -jour t1-结节病的肺移植：结果和预后因素JF-欧洲呼吸杂志JO -EUR RESSIR J DO -10.1183/13993003.033358-2020 VL -58 IS -2 SP -2 SP -2003358 AU -LE PAVEC，Jérôme -vale y -valeyryerre，jérôme -valeyryerre，Dominique AU - Gazengel, Pierre AU - Holm, Are M. AU - Schultz, Hans Henrik AU - Perch, Michael AU - Le Borgne, Aurélie AU - Reynaud-Gaubert, Martine AU - Knoop, Christiane AU - Godinas, Laurent AU - Hirschi, Sandrine AU - Bunel, Vincent AU - Laporta, Rosalia AU - Harari, Sergio AU - Blanchard, Elodie AU - Magnusson, Jesper M. AU - Tissot, Adrien AU - Mornex, Jean-François AU - Picard, Clément AU - Savale,Laurent Au -Bernaudin，Jean -FrançoisAu -Brillet，Pierre -Yves Au -Nunes，Hilario Au -Hunbert，Humbert，Marc Au -Fadel，Elie Au -Gottlieb，Jens Y1- 2021/2021/08/01 UR -HTTP：// http：// erj。erersjournals.com/content/58/2/2/2003358.Abstract N2-在结节病，过去和持续的免疫抑制治疗方案，移植和Extrant的复发性疾病中的患者中的研究问题腹腔受累可能会影响肺移植的结果。我们询问结节病肺表型是否可以分化，如果是的话，它们与通过肺移植治疗的肺结节病患者的结局如何相关。患者和方法我们回顾了112例来自国际诊断标准的患者的数据，这些患者来自国际诊断标准和肺部或肺部的肺病或肺部诊断标准。2006年至2019年在16个欧洲中心之间进行的心脏 - 肺移植。分子患者的生存是主要的结局措施。在移植时，中位数（四分位数（IQR））年龄为52（46-59）岁。71（64％）是男性。肺表型被个性化，如下：1）仅扩展纤维化；2）气流阻塞； 3) severe pulmonary hypertension (sPH) and airflow obstruction; 4) sPH, airflow obstruction and fibrosis; 5) sPH and fibrosis; 6) airflow obstruction and fibrosis; 7) sPH; and 8) none of these criteria, in 17%, 16%, 17%, 14%, 11%, 9%, 5% and 11% of patients, respectively. Post-transplant survival rates after 1, 3, and 5 years were 86%, 76% and 69%, respectively. During follow-up (median (IQR) 46 (16–89) months), 31% of patients developed chronic lung allograft dysfunction. Age and extended lung fibrosis were associated with increased mortality. Pulmonary fibrosis predominating peripherally was associated with short-term complications.Answer to the study question Post-transplant survival in patients with pulmonary sarcoidosis was similar to that in patients with other indications for lung transplantation. The main factors associated with worse survival were older age and extensive pre-operative lung fibrosis.Post-transplant survival in patients with pulmonary sarcoidosis was similar to that in patients with other indications for lung transplantation. The main factors associated with worse survival were older age and extensive pre-operative lung fibrosis. https://bit.ly/2XBfJd6 ER -