Ty -jour t1-根据国民收入JF的多药耐药性结核病的治疗变化 - 欧洲呼吸杂志JO -EUR RESSIR J DO -10.1183/139993003.01394-2020 VL -56 IS -5 SP -5 SP -2001394 AU -KWAK -KWAK,NAKWON AU- KWAK,NAKWON AU -KWON AU--冬季,尼古拉斯·澳 - 坎贝尔,乔纳森·R。-2020/11/01 ur -http://www.qdcxjkg.com/content/56/5/5/5/2001394.abstract N2-本研究的目的是分析治疗的时间变化,以抗多药的结果和结果(MDR)(MDR)(MDR))/抗利Fampin(RR) - 结核病(TB)在国家经济状况的背景下。我们分析了由MDR/RR-TB患者在MDR-TB治疗中对个人患者数据的合作组收集的数据来自37个国家。数据按三个国民收入水平(低/下中间,上层和高)进行了分层,并按治疗时间开始(2001- 2003年,2004- 2004- 2004年,2007年,2007- 2007- 2009年,2010年,2010- 2012年和2013 - 2015年)。分析了研究期间的时间趋势。随着时间的推移,使用具有随机效应的广义线性混合模型计算了不同收入组的治疗成功率。在分析中,总共包括9036名患者。在研究期间,世界卫生组织推荐的A组药物(左氧氟沙星/莫西法沙星,Bedaquiline和lineZolid)的使用增加了,所有收入组的治疗结果都得到了改善。在2001 - 2003年至2013 - 2015年之间,在低/下中部收入国家/地区中,中高中国家的治疗成功率从60%增加到78%,从40%增加到67%,从73%,从73%增加到81%高收入国家的%。 In earlier years, the probability of treatment success in upper-middle-income countries was lower than that in low-/lower-middle-income countries, but no difference was observed after 2010. However, high-income countries had persistently higher probability of treatment success compared to upper-middle income countries.Improved treatment outcomes and greater uptake of group A drugs were observed over time for patients with MDR/RR-TB at all income levels. However, treatment outcomes are still unsatisfactory, especially in upper-middle-income countries.Introduction of group A drugs is probably responsible for improved outcomes, even in resource-poor countries. However, a gap in treatment outcomes, which could not be fully explained by group A drugs, persists between high- and upper-middle-income countries https://bit.ly/2XJpO8U ER -