TY - T1的日常身体活动的比较vity profiles between adults with severe asthma and healthy controls JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02219-2019 VL - 56 IS - 1 SP - 1902219 AU - Neale, Jill AU - Orme, Mark W. AU - Majd, Sally AU - Chantrell, Stacey AU - Singh, Sally J. AU - Bradding, Peter AU - Green, Ruth H. AU - Evans, Rachael A. Y1 - 2020/07/01 UR - //www.qdcxjkg.com/content/56/1/1902219.abstract N2 - Severe asthma is associated with a substantial burden of disease, including premature death and reduced quality-adjusted life years [1]. Care in specialist centres is associated with reduced exacerbation rates and healthcare utilisation, but at the cost of increased use of systemic steroids and increased body mass index (BMI) [2]. Common comorbidities, such as metabolic syndrome and type 2 diabetes are associated with low levels of moderate–vigorous physical activity (MVPA) [3]. Guidelines recommend that adults accumulate either ≥150 min of moderate intensity activity or ≥75 min of vigorous intensity activity per week, accumulated in bouts of any length [4]. Adults with severe asthma may avoid MVPA due to negative expectations and fear-avoidance beliefs [5]. A few small studies have reported that daily step count and time spent in MVPA may be reduced in adults with severe asthma compared to controls [6–8]. However, results are conflicting when physical activity levels are adjusted for confounders such as age, gender, obesity and smoking [7]. Furthermore, adults with severe asthma have reduced health-related quality of life (HRQoL), but whether physical activity levels impact on HRQoL is unknown [9].Compared to controls, adults with severe #asthma attain fewer daily steps and reduced sustained moderate–vigorous #physicalactivity which are associated with worse quality of life. Physical activity and #exercise interventions are needed for severe asthma. http://bit.ly/2W8c7Qa ER -