Ty -jour t1-怀孕期间和产后有活性结核病的风险增加:瑞典JF的基于登记册的队列研究 - 欧洲呼吸杂志JO -EUR RESSIR J DO -10.1183/13993003.01886-2019 SP -1901886 AU -JONSSON,JONSSON,JONSSON,JORKER -JERKER AU- JERKER AU--Kühlmann -Berenzon,Sharon au -Berggren,Ingela au -Bruchfeld,Judith Y1-2019/01/01 UR -http://www.qdcxjkg.com/content/content/early/early/early/2019/12/12/12/12/13993003.011888886-2011919.01886-2019.ABS.ABSBERT N22- 研究与怀孕相关的活性结核风险(TB)的理由研究尚不确定。我们的目的是在瑞典的一项大型回顾性登记群体研究中调查这种风险。从瑞典在瑞典出生的15-49岁妇女的数据数据是从国家分娩登记册中提取的,并与国家TB链接了登记。队列时间分为三个暴露期:在怀孕期间,产后六个月,既不怀孕也不是产后时间。我们在每个时期计算每100 000人年的发病率(IR),而发病率比(IR)均未怀孕或产后作为参考。归因于649 342名妇女,其中553名被注册为活性案例TB:389当怀孕和产后既不怀孕时,怀孕期间有85例,产后79。总体IR分别为每100 000人年的9例,12例和17例,在怀孕期间的发病率比(IRR)为1.4(95%CI 1.1-1.7)和1.9(95%CI 1.5-2.5)。原产国的结核病发生率分层表明,增加的风险集中在TB发病率100或更高的国家的妇女中,而每10万人年龄的发病率率为137,当时怀孕和产后均未发生137,怀孕期间182岁,产后233例.Conclusion We show a significant increase in risk of active TB during both pregnancy and postpartum in women from high incidence countries and recommend TB screening in pregnant women belonging to this risk group.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Jonsson has nothing to disclose.Conflict of interest: Dr. Kühlmann-Berenzon has nothing to disclose.Conflict of interest: Dr. Berggren has nothing to disclose.Conflict of interest: Dr. Bruchfeld has nothing to disclose. ER -