抽象
COVID-19的幸存者可能是心血管发病率和死亡率的风险增加,应仔细监测https://bit.ly/2UhVjoy
给编辑:
COPD的急性恶化(AECOPD)或“COPD危” [1],在COPD的自然病程的关键事件。虽然他们可以在任何阶段的严重程度发生,其影响随着患者出现更严重的气流受限。
一些研究表明,慢性阻塞性肺病急性加重的发生增加了心肌梗死和中风的风险[2],所有原因的[3,4]和心血管死亡[五],在后加重期,尤其是在与AECOPD相关性肺炎[6]。这是最好用K证明unisaki等。[7在距离超过16千术之巅审判中度慢性阻塞性肺病和提高心血管风险数据的预先指定的分析。Ťhe authors found that the hazard ratio for cardiovascular events was increased, particularly in the first 30 days after the exacerbations (HR 3.8, 95% CI 2.7–5.5). The risk increased more than two-fold if the exacerbations led to a hospitalisation; in this case, the hazard ratio reached 9.9 (95% CI 6.6–14.9). This study was important because all deaths were analysed by a clinical end-point committee. There was an unusually high number of cardiovascular events occurring after the exacerbations, suggesting some vascular dysfunction leading to myocardial infarction, stroke and pulmonary embolism.
这个场景似乎是类似报道出现以下住院肺炎,尤其是老年人[8-10]。
当前冠状病2019(COVID-19)大流行主要影响成人和特别是那些受一种或多种慢性疾病[11]。由于严重的COVID-19的大多数情况下是由于肺炎合并呼吸衰竭相关的[11,12],它是可能的,类似的,对COPD患者和/或社区获得性肺炎的病情加重,COVID的幸存者将在心血管事件和死亡率以下疾病的急性期的高风险。We would like to call attention to this vulnerable period, and recommend that patients be closely followed with a management plan that pays special attention to the prompt recognition of cardiovascular complications, especially in the 30 days following the resolution of the acute phase of the event. It would be a pity that those survivors of COVID-19 pneumonia, would then succumb from a relatively preventable consequence.
可共享PDF
脚注
利益冲突:B.切利报道阿斯利康个人费用和研究设施,从葛兰素史克公司,勃林格殷格翰,诺华,赛诺菲和Menarini提交作品外顾问个人的费用。
利益冲突:L.M.法布里报告个人费用和阿斯利康,基耶西,葛兰素史克,诺华,勃林格殷格翰公司和赞邦,从Lusofarmaco个人费用非金融的支持,提交作品之外。
- 收到2020年3月19日。
- 公认2020年3月19日。
- 版权所有©ERS 2020
这篇文章是开放存取并根据知识共享188滚球软件署名非商业许可证4.0的条款分发。