Extract
Asthma is the most frequent immune-mediated chronic condition among children, and is associated with genetic risk factors as well as specific prenatal and early-life exposures [1]. Gastro-oesophageal reflux disease (GORD) is a common paediatric condition [2], associated with bronchospasms in infants, and has been considered a possible risk factor for the development of asthma, although the results are inconsistent [2, 3]. The treatment for GORD is based on acid-suppressive medications, mainly proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) [4].
Abstract
Exposure to acid-suppressive medications in the first year of life is associated with a marked increase in the risk of developing childhood asthma; further studies are required to assess the causal relationship that underlies this association https://bit.ly/2BdAzaJ
Footnotes
Conflict of interest: C. Barbiellini Amidei has nothing to disclose.
Conflict of interest: R. Comoretto has nothing to disclose.
Conflict of interest: L. Zanier has nothing to disclose.
Conflict of interest: D. Donà has nothing to disclose.
Conflict of interest: A. Cantarutti has nothing to disclose.
Conflict of interest: C. Canova has nothing to disclose.
- Received January 8, 2020.
- Accepted May 25, 2020.
- Copyright ©ERS 2020