Extract
We read with great interest a research letter by Pannu et al. [1] in the European Respiratory Journal describing unexpected high mortality results in association with transbronchial lung cryobiopsy (TBLC). The team at Vanderbilt University Medical Center has decided to no longer provide TBLC for inpatients with acute diffuse parenchymal lung disease (DPLD) exacerbations, and spotlighted bleeding complications as a predictive factor for a higher risk of mortality for all patients [1].
Abstract
Lung surface photos show wounds/haemorrhages caused by transbronchial lung cryobiopsy (TBLC). TBLC bleeding can extensively soil airways with consequences for lung function, stressing the need for bleeding prevention and more research via registries. https://bit.ly/34wWAeR
Footnotes
Conflict of interest: A. Bourdin reports grants, personal fees for advisory board work, non-financial support for meeting attendance and has been investigator for AstraZeneca, GSK and Boehringer Ingelheim, personal fees for advisory board work, non-financial support for meeting attendance and has been investigator for Novartis, Chiesi Farmaceuticals and Actelion, personal fees for advisory board work and has been investigator for Teva, Regeneron and Roche, and has been investigator for Gilead, outside the submitted work.
Conflict of interest: M. Romagnoli reports grants and personal fees from AstraZeneca, GSK, Roche and Novartis, grants from Boehringer, Menarini, Chiesi and Alfasigma, personal fees from Guidotti, outside the submitted work.
Conflict of interest: A.S. Gamez has nothing to disclose.
Conflict of interest: K. Hireche has nothing to disclose.
Conflict of interest: J.P. Berthet has nothing to disclose.
Conflict of interest: J.P. Mallet has nothing to disclose.
Conflict of interest: I. Vachier has nothing to disclose.
Conflict of interest: S. Nava has nothing to disclose.
Conflict of interest: P. Reynaud has nothing to disclose.
Conflict of interest: N. Molinari has nothing to disclose.
Conflict of interest: C. Suehs has nothing to disclose.
- Received December 16, 2019.
- Accepted April 7, 2020.
- Copyright ©ERS 2020