Total subjects |
2348 (100%) |
1824 (100%) |
|
Males |
1129 (48.1%) |
839 (46.0%) |
0.181 |
Age <75 years |
2054例(87.5%) |
1314 (72.0%) |
<0.001 |
Treatment completed |
1971 (83.9%) |
1438 (78.8%) |
<0.001 |
Any adverse event leading to permanent discontinuation of treatment |
281 (12.0%) |
172 (9.4%) |
0.009 |
Hepatotoxicity leading to permanent discontinuation of treatment |
18 (0.8%) |
35 (1.9%) |
0.001 |