Extract
Tuberculosis (TB) remains a major global health problem. Inadequate exposure to TB drugs constitutes one of the main factors underlying suboptimal treatment response and development of resistance, as evidenced by results from: thein vitrohollow fibre model [1]; clinical studies on relationships between drug concentrations and response [2–5]; a pharmacogenetic trial [6]; and a recent meta-analysis [7].
Abstract
Quality control in TB drug measurement is essential for the development of new drugs and for patient carehttp://ow.ly/KxWNc
Footnotes
Conflict of interest: Disclosures can found alongside the online version of this article atwww.qdcxjkg.com
- ReceivedSeptember 26, 2014.
- Accepted2015年2月9日。
- Copyright ©ERS 2015