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The associations between atmospheric ozone pollution and increased risks of respiratory diseases have been well established [1, 2], but the underlying biological mechanisms are yet fully ascertained. Lung epithelial cells may be injured by inhaled ozone, but the results were not fully consistent [3, 4]. Furthermore, respiratory microbiota and metabolic homeostasis were deemed as key factors in maintaining human respiratory health, and any disturbances in this balance have the potential to increase the susceptibility to respiratory infectious diseases [5]. However, few human studies have investigated the potential effects of ozone inhalation on respiratory microbiota and metabolome.
Footnotes
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兴趣冲突:王博士没有披露。
Conflict of interest: Mr. Wang has nothing to disclose.
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- ReceivedDecember 17, 2019.
- 公认April 5, 2020.
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