抽象的
进行了对外源性脂质肺炎(ELP)的全国回顾性研究,以更新该疾病的数据,重点是胸廓计算断层扫描(CT)扫描和支气管肺泡灌洗(BAL)调查结果。纳入标准是:1)与ELP诊断相容的异常成像特征的存在;2)肺脂脂质的存在;3)脂质肺炎的外源起源。包括四十四种病例(20名男性和24名女性;平均年龄为62 +/- 11 YRS),其中四个是职业(在工业环境中慢性吸入切割雾或油性蒸汽)。对于用于治疗便秘的液体石蜡的抽吸有30例有关。在34名患者(77%)中存在可能有利的病症,最常见的胃肠道反流(n = 20)和神经学或精神疾病(n = 14)。发烧(39%),减肥(34%),咳嗽(64%),呼吸困难(50%)和裂缝(45%)是最常见的症状。BAL在39例中进行:23%有淋巴细胞静脉炎;14%中性粒细胞炎; and 31% a mixed alveolitis (lymphocytic and neutrophilic). Alveolar consolidations (57%), ground glass opacities (39%), and alveolar nodules (23%) were the most common radiological abnormalities. The changes were bilateral (79%), predominant in the posterior and lower zones of the lobes concerned (74%), hypodense (71%), and spared the subpleural zones (52%). In 13 cases, hypodensity was retrospectively established on CT scan by the presence of a "positive angiogram". This sign may be of diagnostic value when the density measurement is either not possible or not reliable. In conclusion, this study provides an update of the clinical, biological and radiological profile of exogenous lipid pneumonia and, in particular, confirms the diagnostic benefit of computed tomography scan, which revealed bilateral and hypodense changes in a large majority of cases.