抽象的
检测夜间低氧血症,定义为平均动氧饱和度低于90%,常见氧化或轻度缺氧慢性阻塞性肺疾病(COPD)患者似乎临床相关,因为该特征可能先患有肺动脉高血压。夜间研究是昂贵且耗时的程序。目前的研究调查了在多大程度上可以预测来自白天参数的夜间低氧血症。四十二次COPD患者患有日间动脉氧气张力(PAO2)以上8 KPA参加。测量夜行氧化,白天血气值和对高腺炎的通风反应。在10名患者中,发生足够的去污染,符合夜间低氧血症。它们具有明显较低的白天PAO2价值,稳态稳态高型通气响应较低。他们还经常吸烟,并抱怨白天嗜睡。多次线性回归分析表明,白天PAO2(32%)是最佳的独立预测因子。嗜睡(12%)和烟熏的卷烟数量(5%)也贡献独立,但在轻微的方式下贡献。 Patients with a high daytime PaO2 (> 11 kPa) did not develop nocturnal hypoxaemia. The hypercapnic ventilatory response was used to distinguish nocturnal hypoxaemic from normoxaemic patients. Only patients with a low response (< 3.5 l.min-1.kPa-1) appeared to run a risk of developing nocturnal hypoxaemia. The sensitivity of this test was 80%, and the specificity 70%. It is concluded that daytime PaO2, hypercapnic ventilatory response and sleepiness are helpful in predicting nocturnal hypoxaemia.