抽象
Background and objectives胸膜感染是成人发病率和死亡率的主要原因。违规生物的鉴定是适当抗微生物治疗的关键。不知道胸膜感染的微生物模式是否在时间上或地理上是可变的。该系统审查旨在调查可用文献,了解全球微生物学模式以及可能影响此类模式的因素。
数据来源和资格标准在2000年至2018年期间寻找OVID MEDLINE和EMBASE用于报告成人胸膜感染的微生物学的出版物。包括观察和介入研究。如果报告的主要重点是儿科人口,结核病脓肿或术后脓胸,则排除了研究。
研究评估和合成方法包括≥20例清楚报告微生物分离株的患者的研究。从包括的研究中将每个特定生物/组的分离株的数量来自于包括的研究。除了整体呈现数据外,亚组通过地理分布,感染设置分析(社区versus医院)和报告的时间进行了处理。
结果从初始搜索返回的20个报告中,75篇关于10 241名患者的文章被列入数据合成中。全世界最常见的有机体是金黄色葡萄球菌. Geographically, pneumococci and viridans streptococci were the most commonly reported isolates from tropical and temperate regions, respectively. The microbiological pattern was considerably different between community- and hospital-acquired infections, where more Gram-negative and drug-resistant isolates were reported in the hospital-acquired infections. The main limitations of this systematic review were the heterogeneity in the method of reporting of certain bacteria and the predominance of reports from Europe and South East Asia.
ConclusionsIn pleural infection, the geographical location and the setting of infection have considerable bearing on the expected causative organisms. This should be reflected in the choice of empirical antimicrobial treatment.
抽象
金黄色葡萄球菌is the predominant cause of pleural infection in adults with a temporal rise in rate of isolation of the drug-resistant organism. There are variations in the microbiology according to geographical location and setting of infection.http://bit.ly/31wnpi0.
脚注
本文提供了补充材料www.qdcxjkg.com
此系统审查已注册www.crd.york.ac.uk/prospero注册号码CRD42017076418。
支持声明:M. Hassan是欧洲呼吸协会长期研究团契的收件人(2016年7333)。188bet官网地址T. Cargill被美国国家卫生研究所和临床医生的康复信托博士培训奖学金(授予211042 / z / 18 / z)作为学术临床研究员。本文的资助信息已存入CrossRef Finder注册处。
Contribution details: J.P. Corcoran, I. Psallidas and N.M. Rahman conceived the review. E. Harriss and M. Hassan performed the literature search. M. Hassan, J.P. Corcoran, R. Asciak, R.M. Mercer and N.M. Rahman discussed and agreed on inclusion and exclusion criteria. M. Hassan, T. Cargill, R. Asciak and E.O. Bedawi screened publications for eligibility. M. Hassan and T. Cargill extracted, combined and analysed data. M. Hassan wrote the first version of the manuscript. N.M. Rahman, J.P. Corcoran and R.M. Mercer critically reviewed the manuscript. All authors reviewed and approved the final manuscript.
Conflict of interest: M. Hassan has nothing to disclose.
利益冲突:T. Cargill没有什么可以披露的。
兴趣冲突:E.哈里斯没有什么可披露的。
利益冲突:R. Asciak无需披露。
Conflict of interest: R.M. Mercer has nothing to disclose.
Conflict of interest: E.O. Bedawi has nothing to disclose.
Conflict of interest: D.J. McCracken has nothing to disclose.
利益冲突:I. Psallidas没有什么可披露的。
利益冲突:J.P. Corcoran无需披露。
利益冲突:N.M.Rahman无需披露。
- 收到March 16, 2019.
- AcceptedJune 14, 2019.
- 版权所有©ers 2019