年龄 |
74±6 |
72±6 |
0.389 |
性别男性 |
16(73) |
13 (100) |
0.039 |
吸烟习惯 |
|
|
|
Never smoked |
2(9) |
1(8) |
- |
Former or current smoker |
20(91) |
12(92) |
- |
Smoking duration pack-years |
50(35–60) |
50(40–80) |
0.103 |
心血管合并症 |
|
|
|
Coronary heart disease |
17(77) |
8 (62) |
0.319 |
Hypertension |
10(77) |
21(96) |
0.096 |
pulmonary function |
|
|
|
FVC % predicted |
95±12 |
85±14 |
0.029 |
FEV1% 预料到的 |
90±11 |
77±15 |
0.007 |
FEV1/FVC % |
76±8 |
68±10 |
0.025 |
RV % predicted |
98±9 |
101±15 |
0.457 |
TLC % predicted |
94±10 |
84±9 |
0.008 |
RV/TLC % |
42±4 |
44±7 |
0.379 |
FRC % predicted |
98±12 |
95±16 |
0.564 |
dLCO% 预料到的 |
30±8 |
22±7 |
0.007 |
dLCO/v一个% 预料到的 |
33±10 |
27±9 |
0.050 |
血气分析(环境空气) |
|
|
|
pAO2mmhg |
47±8 |
48±10 |
0.768 |
pACO2mmhg |
32±4 |
33±5 |
0.598 |
sAO2mmhg |
83±10 |
83±9 |
0.984 |
功能性能 |
|
|
|
6-MWD m |
228±108 |
239±82 |
0.789 |
WHO functional class |
|
|
0.832 |
Class III |
18(82) |
11(85) |
|
Class IV |
4(18) |
2(15) |
|
血液动力学 |
|
|
|
Right atrial pressure mmHg |
7±3 |
7±6 |
0.966 |
Mean PAP mmHg |
44±10 |
38±7 |
0.089 |
PAWP mmHg |
9±4 |
9±4 |
0.895 |
Cardiac output L·min-1 |
4.2±1.3 |
4.7±1.0 |
0.274 |
Cardiac index L·min-1·m-2 |
2.2±0.6 |
2.3±0.4 |
0.395 |
PVR dyn·s·cm-5 |
758±362 |
550±178 |
0.062 |
svo2% |
62±8 |
63±8 |
0.577 |
pH的药物治疗 |
|
|
|
Phosphodiesterase-5 inhibitors |
22(100) |
13 (100) |
- |
Endothelin receptor antagonists |
4(18) |
1(8) |
0.392 |