附加文件
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Supplementary tables
Supplementary tables
- ERJ-00221-2020.Table_S1.xlsx-
补充表S1。所有蛋白质的列表,它们的log2fc关于第1天和对应的fdr值。这些数据来自大规模分析未刺激的HPCLS(第1,4,7,10和13天)ex vivoculture.
- ERJ-00221-2020.TABLE_S1A.XLSX.-
补充表S1A。与第13天显着调节的所有蛋白质的列表与第1天相比,它们的LOG2FC相对于不同天(4,7,10和13)的第1天和相应的FDR值。这些数据来自大规模分析未刺激的HPCLS(第1,4,7,10和13天)ex vivoculture.
- ERJ-00221-2020.TABLE_S1B.XLSX.-
Supplementary table S1b. List of all the collagens and MMPs that were detected from day 1, 4, 7, 10 and 13, their Log2FC with respect to day 1 on different days (4, 7, 10 and 13) and corresponding fdr values. These data are from mass spec analysis of unstimulated hPCLS over time (day 1, 4, 7, 10 and 13) inex vivoculture.
- ERJ-00221-2020.TABLE_S2.XLSX.-
Supplementary table S2. List of all the metabolites detected over time in unstimulated hPCLS. The list contains Log2FC with respect to day 1 on different days (4, 7, 10 and 13) and corresponding fdr values. These data are from the metabolomic analysis of the hPCLS.
- ERJ-00221-2020.TABLE_S2A.XLSX.-
补充表S2A。在未仿现的HPCLS中随着时间的推移检测到所有注释代谢物的列表。该列表在不同日内(4,7,10和13)和相应的FDR值中的第1天,列表包含log2fc。这些数据来自HPC的代谢分析
- ERJ-00221-2020.Table_S3.xlsx-
Supplementary table S3. List of all the cell-type specific proteins detected, their Log2FC with respect to day 1 and corresponding fdr values. These data are from mass spec analysis of unstimulated hPCLS over time (day 1, 4, 7, 10 and 13) inex vivoculture that were compared to LGEA database.
- ERJ-00221-2020.Table_S3a.xlsx-
补充表S3A。检测到的所有细胞类型特异性蛋白质的列表,在第13天相比,与第1天相比,它们的LOG2FC相对于第1天和对应的FDR值。这些数据来自大规模分析未刺激的HPCLS(第1,4,7,10和13天)ex vivoculture that were compared to LGEA database.
- ERJ-00221-2020.TABLE_S4.XLSX.-
补充表S4。在载体和TGFβ1处理的HPCL中,在第13天检测到的所有蛋白质的清单。他们的LOG2FC关于车辆处理的第13天HPCLS。这些数据来自车辆和TGFβ1处理的HPCLS(第13天)的质量规范分析ex vivoculture.
- ERJ-00221-2020.TABLE_S4A.XLSX.-
Supplementary table S4a. List of all the proteins that were significantly regulated in TGFβ1 treated hPCLS compared to vehicle-treated hPCLS. These data are from mass spec analysis of vehicle and TGFβ1 treated hPCLS (day 13) inex vivoculture.
- ERJ-00221-2020.Table_S5.xlsx-
Supplementary table S5. List of all the cell-type specific proteins detected, their Log2FC with respect to vehicle-treated hPCLS (day 13) and corresponding fdr values. These data are from mass spec analysis of vehicle and TGFβ1 treated hPCLS (day 13) inex vivo文化并与LGEA数据库进行比较。
- ERJ-00221-2020.TABLE_S6.XLSX.-
Supplementary table S6. These data are from time-course mass spec analysis. Here all the proteins detected are listed. The list is broken into values of each donor and replicate. For example: Day04_F-S-LT21_rep1, refers to changes on day 4 with respect to day 1, in a female (F) donor, that has active smoker status (S), is known as ID LT21 and belongs to replicate. These values are not Log2 transformed, hence a value of 1 means no change, below 1 means a decrease and above 1 means increase with respect to day 1 unstimulated hPCLS.
- ERJ-00221-2020.Table_S7.xlsx-
Supplementary table S7. These data are from vehicle and TGFβ1 treated hPCLS (day 13) mass spec analysis. Here all the proteins detected are listed (NA means not detected in that donor or replicate). The list is broken into values of each donor and replicate. For example: Day04_F-S-LT21_rep1, refers to changes on day 4 with respect to day 1, in a female (F) donor, that has active smoker status (S), is known as ID LT21 and belongs to replicate. These values are not Log2 transformed, hence a value of 1 means no change, below 1 means a decrease and above 1 means increase with respect to day 13 vehicle-treated hPCLS.
- ERJ-00221-2020.TABLE_S8.XLSX.-
Supplementary table S8. Raw values of ELISA measurements of each hPCLS per donor.
- ERJ-00221-2020.Table_S9.xlsx-
补充表S9。载体或TGFβ1刺激后每种HPC1的ELISA测量的原始值。
- ERJ-00221-2020.TABLE_S10.XLSX.-
补充表S10。载体,TGFβ1,MMPI和TGFβ1+ MMPI刺激每种供体的每个HPCLS的ELISA测量的原始值。
- ERJ-00221-2020.Supplement.zip-
斐济码头和非间隙ROI选择
- ERJ-00221-2020.Table_S1.xlsx-