抽象
目的Cumulative evidence indicates that childhood maltreatment (CM) is linked to self-reported asthma and chronic obstructive pulmonary disease. However, the relation between CM and objective measures of lung function as determined by spirometry has not yet been assessed.
方法在来自一般人群的1386名成人中拍摄了医疗历史和肺肺功能。参与者还完成了儿童创伤问卷,用于评估情绪,身体和性虐待以及情感和身体忽视。
结果25.3% of the participants reported at least one type of CM. Among them, use of medication for obstructive airway diseases as well as typical signs and symptoms of airflow limitation were significantly more frequent than in the group without exposure to CM. Although participants with CM had numerically lower values for FEV1, FVC and PEF than those without, these differences were non-significant when accounting for relevant covariates like age, sex, height and smoking. Likewise, there were no differences in the FEV1/FVC ratio nor in the frequency of airflow limitation regardless of its definition. No specific type of CM was related to spirometrically determined parameters of lung function.
ConclusionsOur findings call into question the association of CM with obstructive lung diseases as indicated by prior research relying on self-reported diagnoses. We consider several explanations for these discrepancies.
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Conflict of interest: Dr. Yan reports grants from National Institutes of Health, during the conduct of the study;.
兴趣冲突:斯皮泽斯博士无需披露。
利益冲突:Ewert博士讲话讲座德国,詹森德国,奥姆特,阿斯利康,拜耳,GSK,诺华和Boehringer Ingelheim讲座。参与咨询委员会咨询委员会的费用,GS和Novartis。。
利益冲突:Völzke博士没有披露。
利益冲突:Frenzel博士无需披露。
Conflict of interest: Dr. Felix has nothing to disclose.
利益冲突:Lübke博士没有披露。
利益冲突:Grabe博士报告来自Fresenius医疗保险的赠款和个人费用,来自德国研究基金会(DFG)的德国研究基金会(DFG)提供的,曼森·辛格的个人费用,德国研究基金会(DFG),德国教育和研究资助的个人费用(BMBF),来自潮湿基础的补助金,欧盟联合程序神经退行性障碍(JPND)的补助金,来自欧洲社会基金(ESF),在提交的工作之外。
- 收到2020年7月23日。
- Accepted10月7日,2020.
- 复制right ©ERS 2020