tyjour T1 -儿童虐待与肺功能:发现大众JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02882 -2020欧元SP - 2002882 AU -斯皮策,Carsten盟,Ewert拉尔夫盟——Volzke亨利AU -夫兰泽尔,Stefan AU - Felix,斯蒂芬b . AU - Lubke劳拉盟——主观能动性,Hans J. Y1 - 2020/01/01 UR - //www.qdcxjkg.com/content/early/2020/10/15/13993003.02882-2020.abstract N2 -客观累积证据表明，儿童虐待(CM)与自我报告的哮喘和慢性阻塞性肺病有关。然而，CM与肺活量测定法测定的肺功能的客观指标之间的关系尚未得到评估。方法对1386例普通人群进行病史及肺功能测定。参与者还完成了童年创伤问卷，以评估情感、身体和性虐待以及情感和身体忽视。结果25.3%的参与者报告至少一种类型的CM。其中，使用药物治疗阻塞性气道疾病以及气流受限的典型体征和症状明显多于未接触CM组。尽管有CM的参与者的FEV1、FVC和PEF数值比没有CM的参与者低，但当考虑到相关的协变量如年龄、性别、身高和吸烟情况时，这些差异并不显著。同样，无论FEV1/FVC的定义如何，FEV1/FVC的比值和气流限制的频率均无差异。没有特定类型的CM与肺活量测定的肺功能参数相关。结论:我们的发现对CM与阻塞性肺病之间的关系提出了质疑，这与之前的研究依赖于自我报告的诊断。 We consider several explanations for these discrepancies.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Yan reports grants from National Institutes of Health, during the conduct of the study;.Conflict of interest: Dr. Spitzer has nothing to disclose.Conflict of interest: Dr. Ewert reports lectures fees for Actelion Germany, Janssen Germany, OMT, AstraZeneca, Bayer Vital, GSK, Novartis and Boehringer Ingelheim. Fees for participation on Advisory Board for Actelion, GS and Novartis. .Conflict of interest: Dr. Völzke has nothing to disclose.Conflict of interest: Dr. Frenzel has nothing to disclose.Conflict of interest: Dr. Felix has nothing to disclose.Conflict of interest: Dr. Lübke has nothing to disclose.Conflict of interest: Dr. Grabe reports grants and personal fees from Fresenius Medical Care, personal fees from Neuraxpharm, personal fees from Servier, personal fees from Janssen Cilag, grants from German Research Foundation (DFG), grants from German Ministry of Education and Research (BMBF), grants from DAMP Foundation, grants from EU Joint Program Neurodegenerative Disorders (JPND), grants from European Social Fund (ESF), outside the submitted work. ER -