Extract
In 2015, in a cohort of immunocompetent adults, we reported PES pathogens (Pseudomonas aeruginosa, extended-spectrum b-lactamase-producingEnterobacteriaceae,and methicillin-resistantStaphylococcus aureus) in 6% of patients with community-acquired pneumonia (CAP) and microbiological diagnosis. We proposed the use of the PES score, as described previously [1], to assess the risk of pneumonia due to PES pathogens. The score was shown to have good accuracy, with an area under the receiver operating characteristic curve (AUC) of 0.754 (0.708–0.801). We therefore decided to investigate the frequency and characteristics of CAP caused by PES pathogens in late elderly (≥80 years old) patients with CAP.
Abstract
This study demonstrates the importance of identifying patients over 80 years old at risk of CAP due to PES pathogens in order to initiate adequate antimicrobial therapyhttps://bit.ly/2zuWPvx
Footnotes
Conflict of interest: C. Cilloniz has nothing to disclose.
Conflict of interest: C. Dominedo has nothing to disclose.
Conflict of interest: H.J. Peroni has nothing to disclose.
Conflict of interest: P. Di Giannatale has nothing to disclose.
Conflict of interest: C. Garcia-Vidal has nothing to disclose.
Conflict of interest: A. Gabarrus has nothing to disclose.
Conflict of interest: A. Liapikou has nothing to disclose.
Conflict of interest: A. Cecato has nothing to disclose.
Conflict of interest: A. Torres has nothing to disclose.
Support statement: This study was supported by CIBER de Enfermedades Respiratorias (CIBERES CB06/06/0028), and by 2009 Support to Research Groups of Catalonia 911, IDIBAPS. C. Cillóniz is the recipient of both the SEPAR fellowship 2018 and a grant from the Fondo de Investigación Sanitaria (PI19/00207). Funding information for this article has been deposited with theCrossref Funder Registry.
- ReceivedMarch 19, 2020.
- AcceptedApril 28, 2020.
- Copyright ©ERS 2020