摘要
1987年1月,由国际癌症联盟(UICC)编制的第四版TNM恶性肺肿瘤分类正式生效。因此,一个统一的全球肺癌分期系统第一次成为可能。为了验证肺癌的新TNM定义,我们对3000例患者的数据进行了前瞻性分析。检查几个项目:1)临床(TNM)和病理(pTNM)确诊分型的一致性;2)各种诊断技术对病理分型的评价价值;3) TNM定义对区分不同预后组的影响。原发肿瘤(T)的临床和病理分型一致的占64%;淋巴结受累(N)符合率为48%;对于远处转移,这一比例为90%,对于分期,这一比例为55%。对于原发肿瘤(T), x线摄影的准确性(59%)与ct(58%)几乎相同。 Both techniques were less precise in determining the extent of lymph node involvement (computed tomography 50%, radiography 43%, correct assessments). The statistically significant differences in prognosis for the various T-, N- and M-categories as well as for the stages could be confirmed. By the new 1987 TNM definitions (4th edition) for lung cancer international conformity became feasible as well as practical, and the improvement in its prognostic relevance provided, therefore, a more reliable basis for establishing guidelines for individual oncological concepts of therapy.