表
-
表格1-
累计使用大麻和烟草到32岁
大麻联合年 总 0 ≤1 > 1 烟草pack-yrs 0 226 208 40 474(49.0) ≤10 35 171 72 278(28.8) >10 23 82 110 215 (22.2) Total 284(29.4) 461(47.7) 222(23.0) 967 百分比值在括号中给出。卡方(4)= 242,p<0.001。
-
表格2-
32岁时使用大麻和烟草与肺功能的关系
受试者n 麻 烟草 系数 95%可信区间 p值 系数 95%可信区间 p值 FEV1毫升 919 4 -3.7-11.8 0.311 -5.0 -10.3 - -0.2 0.061 FVC毫升 919 12.0 3.0 - -21.0 0.009 0.1 -6.0-6.2 0.968 FEV1/ FVC% 919 -0.08 -0.18 - -0.02 0.127 -0.11 -0.18– -0.04 0.003 TLC毫升 883 25.0 13.9 - -36.0 <0.001 7.4 -0.2-14.9 0.057 FRC毫升 884 15.1 4.8-25.4 0.004 10.5 3.5-17.6 0.003 RV毫升 883 12.6 7.0-18.3 <0.001 6.3 2.4-10.1 0.002 [RAWCMH2O·L-1·年代-1 884 0.014 0.002-0.026 0.024 -0.001 -0.01 - -0.01 0.827 小号GAW毫升·s的-1·CMH2Ø-1·L-1 884 -3.3 -5.5 - -1.0 0.005 -1.5 -3.0 - -0.01 0.059 ŤL,CO毫升·敏-1·毫米汞柱-1 841 -0.019 -0.09-0.05 0.589 -0.130 -0.19– -0.07 <0.001 ŤL,CO/V一个毫升·敏-1·毫米汞柱-1·L-1 841 -0.016 -0.03– -0.01 0.003 -0.023 -0.03– -0.01 <0.001 V一个毫升 894 17.8 6.8-28.9 0.002 2.3 -5.2-9.9 0.545 FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume;[RAW:气道阻力;小号GAW:特定气道导率;ŤL,CO:肺一氧化碳转移因子;V一个:肺泡容量。Linear regression analyses of lung function at age 32 yrs using both cannabis and tobacco exposures as predictors. All analyses adjusted for sex and, except for FEV1/ FVC和sGAW,为高度。性分析ŤL,CO也调整为呼出一氧化碳和血液中的血红蛋白。系数小号represent the difference in lung function associated with each joint-year of cannabis or pack-year of tobacco up to age 32 yrs, adjusted for use of the other substance.
-
表3-
非吸烟者32岁时使用大麻与肺功能的关系
受试者n 系数 95%可信区间 p值 FEV1毫升 449 1.5 -16.0-19.0 0.867 FVC毫升 449 17.5 -2.5 - -37.4 0.087 FEV1/ FVC% 449 -0.19 -0.42-0.04 0.100 TLC毫升 433 33.5 9.9 - -57.1 0.006 FRC毫升 434 8.1 -13.1 - -29.4 0.452 RV毫升 433 12.0 -0.3 - -24.4 0.057 [RAWCMH2O·L-1·年代-1 434 0.029 0.001-0.057 0.042 小号GAW毫升·s的-1·CMH2Ø-1·L-1 434 -6.7 -11.8– -1.7 0.010 ŤL,CO毫升·敏-1·毫米汞柱-1 418 0.032 -0.114-0.178 0.662 ŤL,CO/V一个毫升·敏-1·毫米汞柱-1·L-1 418 -0.019 -0.042-0.004 0.106 V一个毫升 438 28.5 4.3-52.7 0.021 FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume;[RAW:气道阻力;小号GAW:特定气道导率;ŤL,CO:肺一氧化碳转移因子;V一个:肺泡容量。Linear regression analyses of lung function at age 32 yrs using cannabis exposure as the predictor. Analyses are restricted to those without a tobacco smoking history. All analyses adjusted for sex and, except for FEV1/ FVC和sGAW,为高度。性分析ŤL,CO也调整为呼出一氧化碳和血液中的血红蛋白。系数小号represent the difference in lung function associated with each joint-year of cannabis up to age 32 yrs.
-
表格4-
大麻和烟草暴露的纵向分析与肺功能肺功能
受试者n 麻 烟草 系数 95%可信区间 p值 系数 95%可信区间 p值 FEV1毫升 779 4.4 -1.4 - -10.3 0.137 -4.3 -8.2– -0.4 0.031 FVC毫升 779 10.7 3.9-17.5 0.002 0.2 -4.4-4.8 0.928 FEV1/ FVC% 779 -0.07 -0.14-0.01 0.069 -0.09 -0.14– -0.04 0.001 FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. Linear regression analyses of lung function at age 32 yrs using both cannabis and tobacco smoking as predictors, adjusted for lung function at age 15 yrs. Analyses also adjusted for sex, height, change in height between age 15 and 32 yrs, and current asthma at age 32 yrs. Coefficients represent the difference in lung function at age 32 yrs associated with each joint-year of cannabis or pack-year of tobacco up to age 32 yrs, adjusted for the use of the other substance.