抽象
使用不足的抗炎药,如吸入糖皮质激素和色甘酸,可能有助于与哮喘相关的疾病负担。相反地,轻度疾病的积极治疗可能导致避免成本和/或药物的不利影响。本研究的目的是确定在一个大(N = 4909)的儿童随机样本,年龄8-11岁,在澳大利亚新南威尔士州哮喘严重度和吸入皮质类固醇/色甘酸钠使用之间的关系。哮喘及其治疗进行问卷答复进行评估。哮喘,定义为诊断加电流喘鸣,存在于901米的儿童(样品的18%),其中225(5%)具有中度哮喘,定义为哮喘加上额外的症状(睡眠障碍),利用(医院,伤员)或残疾(活动减少,学校不存在)。使用的吸入糖皮质激素/色甘酸钠报告了636名儿童(样本的13%)。使用的决定因素包括:哮喘的诊断,当前的喘鸣和麻烦的干夜间咳嗽。还有抗炎治疗,并为每个孩子建立一个多哮喘的严重程度得分之间有很强的关系。吸入皮质类固醇和/或色甘酸通过用哮喘儿童的56%(每日24%),并通过与中度哮喘(每日42%)的儿童的76%使用。处理不足,小于每日定义为吸入皮质类固醇/色甘酸钠在中度哮喘,在130名儿童(那些患有哮喘或样品的3%的14%)被鉴定。 Conversely, apparently aggressive treatment, defined as inhaled corticosteroid/cromoglycate use in children with persistent minimal symptoms (asthma severity score of less than 3) was identified in 101 children (2% of the sample). Although there were significant differences between regions in the choice of anti-inflammatory drugs and in the prevalence both of undertreatment and apparently aggressive treatment, there was no clear relationship to regional utilization of emergency and hospital services for asthma. Nevertheless, the frequency of undertreatment suggests an opportunity to reduce asthma morbidity by more consistent application of current therapeutic guidelines.