耐心 |
52 |
65 |
|
基线特征 |
|
|
|
Non-Hispanic white ethnicity |
47 (90%) |
53 (82%) |
0.2 |
Age years |
67 (63–69) |
65(63-68) |
0.61 |
Height m |
1.77 (1.75–1.79) |
1.62(1.61–1.64) |
<0.001 |
Weight kg |
74.05 (71.33–77.29) |
56.37 (54.39–58.51) |
<0.001 |
BMI kg·m−2 |
23.54 (22.70–24.37) |
21.42 (20.74–22.13) |
<0.001 |
FEV1% predicted |
79.9 (73.9–85.5) |
73.6(69.2–77.8) |
0.09 |
Prior/ongoing medical treatment |
29 (56%) |
49 (75%) |
0.03 |
Prior surgical resection |
1 (2%) |
4 (6%) |
0.38 |
Selected comorbidities# |
|
|
|
Rhinitis or sinusitis |
25 (48%) |
29(45%) |
0.71 |
Gastro-oesophageal reflux |
26 (50%) |
30 (46%) |
0.71 |
Chronic inhaled steroid use |
11 (21%) |
11 (17%) |
0.64 |
Osteopenia or osteoporosis |
1 (2%) |
34 (52%) |
<0.001 |
胃肠道调查¶ |
|
|
|
Oesophageal dysmotility |
28/41 (68%) |
38/63 (60%) |
0.53 |
Gastro-oesophageal reflux |
22/40 (55%) |
28/62 (45%) |
0.42 |
Oropharyngeal dysphagia |
27/39 (69%) |
32/62 (52%) |
0.1 |
Selected laboratory results |
|
|
|
CFTRgene mutation carriage§ |
4/36 (11%) |
3/36 (8%) |
1 |
Abnormal α1-AT phenotype |
5/46 (11%) |
10/62 (16%) |
0.58 |
Serum vitamin D <30 ng·mL−1 |
17/47 (36%) |
16/59 (27%) |
0.4 |
胸部成像 |
|
|
|
Nodular bronchiectasis |
50 (96%) |
65 (100%) |
0.2 |
Cavitation |
10(19%) |
25 (38%) |
0.03 |
Lobar predominance |
|
|
|
Right upper lobe |
24 (46%) |
19 (29%) |
0.08 |
Right middle lobe |
25 (48%) |
47 (72%) |
0.01 |
Right lower lobe |
16 (31%) |
22 (34%) |
0.84 |
Left upper lobe |
11 (21%) |
5 (8%) |
0.06 |
Lingula |
21(40%) |
36 (55%) |
0.14 |
Left lower lobe |
8 (15%) |
11 (17%) |
1 |
Pectus excavatum |
|
|
|
Haller index |
2.17(2.09–2.27) |
2.27 (2.18–2.38) |
0.15 |
Haller index >2.5 |
10(19%) |
18 (28%) |
0.38 |
Correction index |
6.58 (5.42–8.11) |
6.95 (5.99–8.15) |
0.68 |
Correction index >10 |
10(19%) |
12(18%) |
1 |
Scoliosis and kyphosis |
|
|
|
PA棒子b angle |
6.01° (4.86–7.53°) |
8.20° (6.90–9.80°) |
0.04 |
PA棒子b angle >10° |
10(19%) |
23 (35%) |
0.06 |
Lateral Cobb angle |
47.34° (44.64–50.31°) |
45.14°(42.44–48.36°) |
0.31 |