Extract
Volatile organic compounds (VOCs) such as benzene, toluene, ethylbenzene, xylenes and styrene (BTEXS) and trihalomethanes are carbon-containing chemicals that readily evaporate at room temperature [1]. VOCs are ubiquitous, mainly in indoor environments, but are also present outdoors, and are commonly found in cigarettes, degreasers, solvents, detergents, deodorisers, paints, furniture, pesticides and personal care products [1]. Additionally, trihalomethanes travel into the air when showering with chlorinated water or washing dishes [1]. Due to inhalation being the main route of exposure to VOCs, these chemicals have raised concerns for respiratory health [2]. In vitro and animal experimental studies have shown that VOCs such as chlorobenzene, styrene and xylene have been shown to trigger inflammation in lung epithelial cell lines [3].
Abstract
In this study sample representative of the US adult population, blood xylenes, bromodichloromethane and dibromochloromethane are associated with non-reversible airflow obstruction, whereas blood styrene is associated with reversible airflow obstruction https://bit.ly/3ybdyQa
Footnotes
Data sharing: A. Mendy takes full responsibility for the integrity of the dataset and the analysis results. The SAS codes and datasets will be made available for the sole purpose of reproducing the findings upon request.
Conflict of interest: A. Mendy's contribution is funded in part by NIEHS grant P30ES006096. Outside the submitted work, A. Mendy has no further disclosures. A.L. Merianos reports grants from National Institute on Drug Abuse (K01DA044313), National Institute of Environmental Health Sciences (R21ES032161, R01ES030743, R01ES027815). There are no further disclosures.
Support statement: This work was supported in part by the National Institute on Drug Abuse (grant number K01DA044313), the National Institute of Environmental Health Sciences (grant numbers R21ES032161, R01ES030743, R01ES027815, P30ES006096, R01ES030743, R01ES027815 and P30ES006096), National Heart, Lung, and Blood Institute (grant number R01HL132344), and National Human Genome Research Institute (grant number R01HG011411) of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Funding information for this article has been deposited with the Crossref Funder Registry.
- Received May 24, 2022.
- Accepted September 25, 2022.
- Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org