主题 |
91 |
77 |
98 |
|
男性 |
19(27.9) |
19(25.0) |
21(25.3) |
0.91 |
年龄 |
65(51–75) |
63(53–73) |
64(54–74) |
0.83 |
当前/前吸烟者 |
32(47.1) |
36(47.4) |
32(38.6) |
0.45 |
BMI KG·M-2 |
23.2(20–26) |
22(18.9–25.0) |
21(19.4–24.5) |
0.15 |
疾病的严重程度 |
|
|
|
|
BSI |
6(4–9) |
7(4-10) |
8(5-12) |
0.009¶ |
Mild |
28(31.1) |
23(29.1) |
17(17.9) |
0.09 |
Moderate |
39(43.3) |
28(35.4) |
35(36.8) |
0.52 |
Severe |
23(25.6) |
28(35.4) |
43(45.3) |
0.02+ |
E-FACED |
2(1-3) |
2(1-3) |
3(1-4) |
0.0006§ |
Mild |
73(84.9) |
55(76.4) |
59(64.8) |
0.008ƒ |
Moderate |
12(14.0) |
12(16.7) |
25(27.5) |
|
Severe |
1(1.2) |
5(6.9) |
7(7.7) |
|
mMRC 3–4 |
6(6.6) |
8(10.4) |
14(14.4) |
0.22 |
合并症 |
|
|
|
|
Cardiovascular diseases |
23(33.8) |
20(26.3) |
27(32.5) |
0.57 |
Chronic renal failure |
2(2.9) |
3(4.0) |
2(2.4) |
0.89 |
Diabetes |
4(5.9) |
8(10.5) |
2(2.4) |
0.11 |
History of pneumonia |
41(60.3) |
48(63.2) |
48(57.8) |
0.79 |
History of tuberculosis infection |
5(7.4) |
8(10.5) |
7(8.4) |
0.79 |
Rheumatoid arthritis |
1(1.7) |
1(1.5) |
1(1.3) |
1.0 |
History of other CTD |
3(5.2) |
0(0.0) |
1(1.3) |
0.11 |
History of IBD |
2(2.9) |
2(2.6) |
0(0.0) |
0.33 |
History of autoimmune disease |
0(0.0) |
2(3.1) |
0(0.0) |
0.19 |
Primary ciliary dyskinesia |
5(8.6) |
6(9.2) |
10(13.0) |
0.66 |
Asthma |
10(14.7) |
12(15.8) |
10(12.1) |
0.79 |
COPD# |
6(8.8) |
7(9.2) |
7(8.4) |
0.99 |
Rhinosinusitis |
24(35.3) |
25(32.9) |
29(34.9) |
0.95 |
Gastro-oesophageal reflux disease |
26(44.8) |
26(40.0) |
35(45.5) |
0.79 |
Primary immunodeficiency |
7(12.1) |
10(15.4) |
13(16.9) |
0.74 |
Secondary immunodeficiency |
2(3.5) |
4(6.2) |
1(1.3) |
0.34 |
临床状况 |
|
|
|
|
Sputum colour |
|
|
|
|
Mucoid |
12(27.3) |
9(16.7) |
6(9.5) |
0.16 |
Mucopurulent |
16(36.4) |
25(46.3) |
27(42.9) |
Purulent/severe purulent |
16(36.4) |
20(37.0) |
30(47.6) |
Sputum volume |
6(5–20) |
15(5–50) |
25(7-75) |
<0.0001## |
Exacerbation previous year |
2(1-3) |
2(1-3) |
2(1-3) |
0.77 |
Patients with ≥2 exacerbations in previous year |
49(54.4) |
47(60.3) |
58(60.4) |
0.65 |
>1 hospitalisation in previous year |
15(16.7) |
12(15.2) |
23(24.0) |
0.27 |
生活质量 |
|
|
|
|
QoLB physical |
59.8±25.1 |
61.1±25.3 |
52.8±27.1 |
0.31 |
QoLB role |
66.7(50–80) |
73.3(46.7–86.7) |
66.7(40–80) |
0.43 |
QoLB vitality |
53.1±19.9 |
51.2±23.5 |
49.8±19.7 |
0.79 |
QoLB emotion |
70.9(58.3–87.5) |
75(66.7–91.7) |
75(50.0–91.7) |
0.83 |
QoLB social |
68.9±23.0 |
59.7±26.6 |
54.7±26.6 |
0.05 |
QoLB treatment burden |
66.7(55.6–77.8) |
66.7(55.6–77.8) |
66.7(44.4–77.8) |
0.86 |
QoLB health |
41.7(20.9-58.3) |
41.7(25–50) |
33.3(16.7–50.0) |
0.33 |
QoLB respiration |
74.1(66.7–81.5) |
70.4(59.3–77.8) |
66.7(51.9-74.1) |
0.04¶¶ |
标准微生物学 |
|
|
|
|
Chronic infection |
26(30.2) |
34(44.7) |
66(71.0) |
<0.0001++ |
Chronic infectionP.铜绿 |
12(14.0) |
21(27.6) |
44(47.3) |
<0.0001§§ |
Chronic infection other bacteria |
16(18.6) |
21(27.6) |
25(26.9) |
0.31 |
FEV1l |
1.9(1.5–2.5) |
1.9(1.4-2.4) |
1.7(1.2–2.1) |
0.02ƒ |
FEV1% |
80.2±24.4 |
74.0±20.0 |
73.0±27.1 |
0.10 |
FEV1<50%预测 |
8(8.9) |
9(12.0) |
22(23.2) |
0.02### |
FEV1<35%的预测 |
2(2.2) |
3(4.0) |
9(9.5) |
0.09 |