抽象
The effects of antibiotic treatment on the results of protected specimen brushing (PSB) in ventilator-associated pneumonia were prospectively assessed by performing this procedure before antibiotic treatment, and 12, 24, 48 and 72 h after initiation of antibiotic treatment, in 35 ventilated patients who developed pneumonia during mechanical ventilation.
分离的微生物的数量,它们的浓度(菌落形成单位(cfu)·毫升-1),以及具有正PSB箱子(≥10数3 cfu·mL-1)进行了评价。
Within 12 h of the initiation of effective antibiotic treatment a rapid, significant decrease in the numbers of organisms isolated, their individual concentrations and the percentage of positive PSB results were observed. Certain bacterial species (肺炎链球菌,嗜血influenzee)似乎更容易受到抗生素比其他人(金黄色葡萄球菌,铜绿假单胞菌,鲍氏不动杆菌)。
这个数据证实,现有抗生素治疗,即使经过唯一的活动的几个小时,显著降低保护刷样品的灵敏度;这种效果似乎是特别显着参与早期呼吸机相关性肺炎的物种。
这项研究是由“丰多科学调查德Sanitarias德拉SEGURIDAD社会”(FIS)没有94/0874获得了资助。
脚注
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