摘要
分析右心室流出道收缩期血流速度曲线(SFVC)被认为是一种替代三尖瓣压力梯度(TVPG)方法的回声多普勒肺动脉压力(P(pa))评估方法。本研究检查了SFVC是否受到肺动脉高压原因的影响。对86例急性(AP-PE)或慢性(CP-PE)近端肺栓塞、慢性阻塞性肺疾病(COPD)或原发性肺动脉高压(PPH)患者(39名女性,年龄55.5+/-15.2岁)的多普勒记录进行回顾性分析,两名不知道研究目的的观察人员进行了分析。AP-PE患者TVPG最低(48+/-13 mmHg),但加速时间最短(t(acc);56+/-15 ms)和收缩中期减速时间(t(msd);105 + / -16 ms)。t(acc) <60 ms的TVPG <60 mmHg患者AP-PE的特异性为98%,敏感性为48%。在PPH中,SFVC的异常较小(t(acc) 64+/-14 ms, t(msd) 125+/-25 ms,两者p<0.03),尽管TVPG是前者的两倍高(92+/-12 mmHg, p< 0.001)。与t(acc)相比,TVPG与直接P(pa)测量值具有很强的相关性(r=-0.43, P =0.02, r=0.80, P <0.001;n = 30)。 There was no correlation between t(acc) and TVPG in a pooled study group and SFVC seemed strongly affected by the presence of both AP-PE and CP-PE. While potentially useful for evaluation of the true right ventricular afterload during pulsatile flow conditions, the systolic flow velocity curve does not provide a reliable estimate of pulmonary arterial pressure.