抽象的
高频输入阻抗(Z(F))测量,包括反谐音,在犬和人类成人呼吸系统中提供有关气道几何形状的有用的非侵入性信息,特别是气道墙体力学。在理解婴儿的流动限制现象方面,对气道墙机械师的认识尤为重要。高频Z(F)尚未在256Hz以上的婴儿中测量,因为婴儿呼吸系统的高阻抗预期导致较高频率下的振荡流量的低幅度。本研究的目的是开发一种方法来测量婴儿的高频Z(F),并阐明婴儿Z(F)光谱中的抗谐波现象的性质。Z(F)在32-900赫兹期间,通过18次婴儿(24-149周龄)的高速中断技术(HIT)在快速的气流中断期间从32-900赫兹中断。使用假脚踏强制功能,命中使得能够在高频下振荡更高的流量幅度。在所有婴儿z(f)中,显示了172(35)Hz的平均值(SD)的第一抗体(FAR,1)(Z(F)的真实部分,1(Z(F)Re(FAR,1)): 4.9 (1.1) kPa x L(-1) x s) and in five infants a second antiresonance (far,2) of 564 (51) Hz (Z(f)re(far,2): 2.0 (0.7) kPa x L(-1) x s). The antiresonances were found to be related to wave propagation in the airways (acoustic antiresonances), because they increased by a factor of approximately 2 when He-O2 was inhaled. This implies that far,1 and its harmonics are a function of airway wall compliance. In conclusion, the first and second antiresonances may be helpful in understanding flow limitation in wheezing disorders in infants, because flow limitation is related not only to airway diameter but also to airway wall compliance.