Extract
We would like to congratulate Hilleret al. for their systematic analysis of cancer occurrence in a large prospective cohort of individuals with severe alpha-1 antitrypsin deficiency (AATD; Pi*ZZ genotype) [1]. The data on development of hepatic cancer are of particular relevance for two reasons: (i) the current evidence is low and controversial [2]; (ii) the early detection of liver cancer is associated with markedly improved prognosis and because of that, surveillance programs are recommended in high risk individuals [3, 4].
Footnotes
This manuscript has recently been accepted for publication in theEuropean Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of theERJonline. Please open or download the PDF to view this article.
Conflict of interest: Malin Fromme has nothing to disclose.
Conflict of interest: Pavel Strnad has nothing to disclose.
- ReceivedApril 6, 2022.
- AcceptedApril 9, 2022.
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