抽象
粘弹性代表了呼吸力学的重要组成部分,负责,在某些情况下,对于大多数的呼吸中消耗的压力。迄今为止可用于确定粘弹特性已被简化的方法,但仍然是时间要求严格,取决于计算的一个很大。在这项研究中,介绍了确定机械通气时呼吸粘弹性特性的简单方法。呼吸系统的粘弹性常数,建模为麦克斯韦体,进行了研究中使用两种吸气末闭塞17名正常人和7例急性肺损伤(ALI);一个具有短吸气时间(TI),以确定粘弹性的弹性部件和另一个具有长TI来评估粘弹性的电阻分量。结果是可再现的和类似于由先前描述的多呼吸法(MB)提供的那些。The mean+/-SD viscoelastic resistance was 5.31+/-1.50 cm H2O x L(-1) x s with the proposed method and 5.71+/-1.87 cm H2O x L(-1) x s with the MB method in normal subjects, and 8.93+/-2.82 cm H2O x L(-1) x s and 10.36+/-3.13 cm H2O x L(-1), respectively in ALI patients. The mean+/-SD viscoelastic elastance was 3.92+/-0.84 cm H2O x L(-1) and 4.94+/-1.01 cm H2O x L(-1) in normal subjects and 7.08+/-2.01 cm H2O x L(-1) and 8.21+/-1.16 cm H2O x L(-1) in ALI patients, respectively. The mean+/-SD viscoelastic time constant was 1.36+/-0.24 s and 1.17+/-0.34 s in normal subjects and 1.26+/-0.35 s and 1.24+/-0.23 in ALI patients, respectively. The method was easy to perform and applicable at the bedside in clinical routine.