60 Results
for term "advanced"
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...EDITORIAL L. Di Candia, R. Saunders and C.E. Brightling mong the pattern recognition receptors (PRRs), the receptor foradvancedglycation end-products (RAGE) has been shown to bind many damage-associated molecular patterns (DAMPs, also known as alarmins). DAMPs are released following tissue damage ...
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...D.J. Smith*,+, S.T. Yerkovich#,+, M.A. Towers*,#, M.L. Carroll#, R. Thomas" and J.W. Upham*,# ABSTRACT: The soluble receptor foradvancedglycation end-products (sRAGE) has antiinflammatory properties, and deficiency of circulating sRAGE is associated with various human diseases. Whether s ...
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...M.B. Sukkar*, L.G. Wood#, M. Tooze#, J.L. Simpson#, V.M. McDonald#,", P.G. Gibson#," and P.A.B. Wark#," ABSTRACT: The receptor foradvancedglycation end-products (RAGE) is a pattern-recognition receptor involved in the host response to injury, infection and inflammation. It is a membrane receptor ...
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...of suitable donor organs. Beyond lung transplantation, several approaches to repair and regenerate lung tissue, with the aim of restoring lung function, have made substantial progress in recent years and hold great promise for future therapies. Importantly,advancementin our understanding of the underlying ...
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...tissue extracts. Sputum levels were uninformative. Unlike C-reactive protein (CRP), PTX3 levels did not increase in COPD, but a correlation between plasma levels and FEV1 was observed, with a decrease in moreadvanceddisease stages. These findings are unexpected and provocative, raising a number ...
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...an important biochemical marker of alveolar epithelial injury, the receptor foradvanced糖化终产物(愤怒)[7]。他们发现海拔高度ated levels of RAGE on days 1 and 2, which correlated with a decrease in alveolar fluid clearance on the same days. Measurement of alveolar fluid clearance (AFC) has ...
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...]. Interestingly, in a phase I study, two out of 13 patients withadvancedMPM who had progressed after first-line chemotherapy demonstrated a partial clinical response after oral administration of SAHA for several cycles of therapy [9]. Among HDAC inhibitors, VPA is known to be less active than hydroxamic acids ...
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.../cytokine levels and histological injury scores). Moreover, mice displayed alveolarcapillary barrier dysfunction/ epithelial injury as reflected by increased alveolar protein, lung wet/dry weight ratio and soluble receptor foradvancedglycation end-products, as well as reduced alveolar fluid clearance ...
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...could contribute to lung fibrosis. 24 MPA patients (45 sera) were enrolled in the study, including nine patients (22 sera) with lung fibrosis. Serumadvancedoxidation protein products (AOPP), MPO-induced hypochlorous acid (HOCl) and serum-induced fibroblast proliferation were assayed. AOPP levels ...
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...for a noninvasive, simple, inexpensive and easy-to-use diagnostic tool [519]. In fact, monitoring VOCs in the breath may soon become an interesting supplement (or even an alternative) to conventional medical diagnostics, thanks to the rapidadvancesin the techniques for breath collection and gas-analysis [5 ...