Bone morphogenetic proteins (BMPs) are dimeric transforming growth factor ß (TGFß) family
cytokines that were first described in bone and cartilage formation but have since been …

的机制giogenic endothelial cells break the physical barrier of the vascular
basement membrane and consequently sprout to form new vessels in mature tissues is …

Acute myeloid leukemia (AML), which is the most common acute adult leukemia and the
second most common pediatric leukemia, still has a poor prognosis. Human C‐type lectin‐like …

Objective— Alpha6 integrin subunit (α6) expression is increased by proangiogenic growth
factors such as vascular endothelial growth factor (VEGF) and fibroblast growth factor. This …

Aims BMP9 and BMP10 mutations were recently identified in patients with pulmonary arterial
hypertension, but their specific roles in the pathogenesis of the disease are still unclear. …

Stauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation
by inhibiting nuclear localization of the MYC transcription factor NME2, which in turn …

Angiogenesis has become an attractive target for cancer therapy. However, despite the initial
success of anti-VEGF (Vascular endothelial growth factor) therapies, the overall survival …

Cancer stem cells (CSCs) have been identified in a growing list of malignancies and are
believed to be responsible for cancer initiation, metastasis and relapse following certain …

The mechanisms underlying pulmonary hypertension (PH) are complex and multifactorial,
and involve different cell types that are interconnected through gap junctional channels. …

Low-molecular-weight fucoidan (LMWF) is a sulfated polysaccharide extracted from brown
seaweed that presents antithrombotic and pro-angiogenic properties. However, its …