Extract
Recent developments in single-cell technologies, and particularly single cell RNA sequencing (sc-RNAseq), have provided invaluable tools to decipher complex biological systems like the lung. In the respiratory system, sc-RNAseq analyses have led to the discovery of new cell types, such as ionocytes, as well as to a refined classification of the cells composing the lung [1–4]. Profiling of more than 300 000 cells from patients suffering of lung pathologies, such as idiopathic pulmonary fibrosis (IPF) has allowed to identify new sub-populations of aberrant basal and endothelial cells that are specific of IPF [5].
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Conflict of interest: Dr. Curras-Alonso has nothing to disclose.
Conflict of interest: Dr. Soulier has nothing to disclose.
Conflict of interest: Dr. Walter has nothing to disclose.
Conflict of interest: Dr. Mueller has nothing to disclose.
Conflict of interest: Dr. Londono Vallejo has nothing to disclose.
Conflict of interest: Dr. Fouillade has nothing to disclose.
- Received November 24, 2020.
- Accepted March 29, 2021.
- Copyright ©The authors 2021. For reproduction rights and permissions contact permissions{at}ersnet.org