Abstract
Introduction:Sometimes it’s not easy have a pathologist to perform ROSE during an EBUS-TBNA procedure. Our objective was to analyze the concordance between ROSE performed by pulmonologists and the definitive pathological diagnosis.
Methods:回顾性分析中执行的EBUS-TBNA our center, from february 2016 to september 2019, in which ROSE was performed by a pulmonologist through a fresh staining with panoptic rapid immersion technique. Results were reported as valid/suggestive, valid/non-suggestive and non-valid/non-suggestive, depending on lymphocytes and atypical cells presence. A comparison with the definitive pathological diagnosis is done, in all cases performed and those in which a malignancy diagnosis was obtained.
Results:453 EBUS-TBNA procedures analyzed in the study period, 198 met study criteria. Average age 64.08, 155 male sex. 437 punctures of hiliomediastinal lymph nodes (LN) were performed, average 3.66 punctures per LN. Punctured LN stations were 7 (n=140), 4R (n=104), 4L (n=58), 11L (n=34), 2R (n=31), 11R (n=29), 10R (n=19), 10L (n=8), 2L (n=8), 8 (n=4) and 3p (n=2). Valid/suggestive result was obtained in 104 patients (52.3%), valid/non-suggestive in 81 (40.9%) and non-valid /non-suggestive in 13 (6.6%). The overall concordance was considered as a moderate degree (kappa index 0.494). Concordance related to malignancy ROSE results (valid/suggestive) is considered as a high degree relation (kappa index 0.952), with sensitivity 98.9%, specificity 92.3% and NPV 92.3%.
Conclusions:ROSE of EBUS-TBNA mediastinal LN cytological samples performed by pulmonologists show a high concordance in case of malignancy results.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 5122.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available atwww.ers-education.org(ERS member access only).
- Copyright ©the authors 2020