Abstract
Validation of the usage of tracheal aspiration considering children with lung disease
This study investigates the usability of nasal tracheal aspiration (NTA) by comparing NTA against bronchoalveolar lavage (BAL)
Methods:对164名儿科患者进行了173个NTA和BAL的配对样品。在全身麻醉期间自发呼吸的患者收集样品。这项研究回顾性比较了NTA和BAL获得的微生物培养物
结果:Concerning complete bacteria concordance the overall similarity is 49%, sensitivity 35%, specificity 66%, positive predictive value 25% and negative predictive value is 65%.
当关注+ / -增长of pathogen bacteria the similarity is 70%, sensitivity 74%, specificity 66%, positive predictive value 74% and negative predictive value 65%.
Patients with cystic fibrosis have statistic significant better parameters than the overall samples regarding similarity 88%, sensitivity 92% and positive predictive value of 92% for +/- growth.
If the common throat bacteria H.influenzae and Moraxella are the only difference between NTA and BAL concerning the bacteria concordance the omission of these improves the statistic significant specificity of 91%.
检查时的抗生素治疗似乎具有提高灵敏度的积极趋势,但是并不重要
Conclusion:The study indicates that NTA is clinically useful to evaluate if the lower airways are colonized or not, but generally not concerning which specific bacteria. The clinically usage of NTA remains important as both positive and negative findings are of great value concerning children with chronic lung diseases
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4791.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available atwww.ers-education.org(ERS member access only).
- Copyright ©the authors 2019