Abstract
在患有肺动脉高压的患者中,妊娠与孕妇死亡的高风险有关。咨询此类患者以避免怀孕,或者如果发生怀孕,则会提早中断。但是,一些患者决定继续怀孕,而另一些患者可能会在怀孕期间首次出现症状。肺血管扩张剂治疗为这些高危患者提供了一种治疗选择。
The present study describes three patients with pulmonary arterial hypertension of various aetiologies who were treated with the prostacyclin analogue iloprost during pregnancy, and the post-partum period.
Nebulised iloprost commenced as early as 8 weeks of gestation and patients were admitted to hospital between 24–36 weeks of gestation. All pregnancies were completed with a duration of between 25–36 weeks and all deliveries were by caesarean section under local anaesthetic. All patients delivered children free from congenital abnormalities, and there was no post-partum maternal or infant mortality.
In conclusion, although pregnancy is strongly advised against in those with pulmonary hypertension, the current authors have achieved a successful outcome for mother and foetus with a multidisciplinary approach and targeted pulmonary vascular therapy.
Footnotes
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