TY - T1的量化评分的interferon-γ分析区分活跃的潜伏性结核病JF -欧洲呼吸杂志》乔和J SP - 722 LP - 728欧元——六世10.1183/09031936.00028507 - 30 - 4 AU - J]。詹森AU - p . Roux-Lombard AU - t . Perneger AU - m . Metzger AU - r .薇薇安AU - t .装置Y1 - 2007/10/01 UR - //www.qdcxjkg.com/content/30/4/722.abstract N2 -本研究的目的是评估的贡献一个interferon-γ释放试验(结核感染t细胞斑点)的分化活动从潜伏结核感染肺结核(TB)量化spot-forming单位(学院)。调查的前瞻性研究接触暴露于传染性结核病和艾滋病毒阴性的病例culture-proven结核病在16个月期间。结核菌素皮肤试验(测试)和T-SPOT。310年结核病进行接触暴露后8 - 12周。在受试者culture-proven结核,T-SPOT。结核病治疗开始的两周内进行。分析包括所有接触积极T-SPOT。结核病的结果和所有科目与结核病。结核病接触者(n = 127)和例(58例)包括在内。均值±sd T-SPOT。TB results were 107±56 (range 1–207) sfu for TB, 54±60 (7–239) sfu for contacts with positive T-SPOT.TB results and a TST induration diameter of >5 mm, and 19±27 (7–143) sfu for contacts with positive T-SPOT.TB results and a TST induration diameter of ≤5 mm. By receiver operating characteristic curve analysis, a threshold value of 49.5 sfu showed a sensitivity of 83% and specificity of 74% for distinguishing latent TB infection from TB. Although T-SPOT.TB results were significantly related to disease activity, the test cannot be recommended for the diagnosis of tuberculosis. ER -