作者@article {Janssens722 = {j]。詹森和p . Roux-Lombard t . Perneger m . Metzger和r .薇薇安和t .装置}title = {interferon-γ分析的量化评分区分积极从潜伏性结核病},体积={30}={4},页面= {722 - 728}= {2007},doi ={10.1183/09031936.00028507},出版商={欧洲呼吸学会},文摘={本研究的目的是评估的贡献一个interferon-γ释放试验(结核感染t细胞斑点)的分化活动从潜伏结核感染肺结核(TB)量化spot-forming单位(学院)。188bet官网地址调查的前瞻性研究接触暴露于传染性结核病和艾滋病毒阴性的病例culture-proven结核病在16个月期间。结核菌素皮肤试验(测试)和T-SPOT。310年结核病进行接触8 {\ textendash} 12周后曝光。在受试者culture-proven结核,T-SPOT。结核病治疗开始的两周内进行。分析包括所有接触积极T-SPOT。结核病的结果和所有科目与结核病。结核病接触者(n = 127)和例(58例)包括在内。意思是{\ textpm} sd T-SPOT。TB results were 107{\textpm}56 (range 1{\textendash}207) sfu for TB, 54{\textpm}60 (7{\textendash}239) sfu for contacts with positive T-SPOT.TB results and a TST induration diameter of \>5 mm, and 19{\textpm}27 (7{\textendash}143) sfu for contacts with positive T-SPOT.TB results and a TST induration diameter of <=5 mm. By receiver operating characteristic curve analysis, a threshold value of 49.5 sfu showed a sensitivity of 83\% and specificity of 74\% for distinguishing latent TB infection from TB. Although T-SPOT.TB results were significantly related to disease activity, the test cannot be recommended for the diagnosis of tuberculosis.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/30/4/722}, eprint = {//www.qdcxjkg.com/content/30/4/722.full.pdf}, journal = {European Respiratory Journal} }