JF - europe respiratory Journal JO - Eur Respir J SP - 436 LP - 442 DO - 10.1173 /09031936.04.00007104 VL - 24 IS - 3 AU - Ong, K-C。AU - Ng, A.W-K。李欧利，L.S-U。AU - Kwek, G. AU - Kwek, S-K.AU - Leow, M.K-S。这项研究的目的是调查一组严重急性呼吸综合征(SARS)幸存者的肺功能和运动能力。在出院3个月后，46名SARS幸存者接受了以下评估:肺活量、静态肺容量和一氧化碳转移因子(TL,CO)。其中44例患者接受了心肺运动试验。23例(50%)患者肺功能检查未见异常。7例(15%)、12例(26%)、1例(2%)和18例(39%)患者的强迫肺活量(FVC)、1秒用力呼气量(FEV1)、FEV1/FVC和TL、CO异常。 All of these abnormalities were mild except in one case. In 18 patients (41%), the maximum aerobic capacity was below the lower limit of the normal range. Breathing reserve was low in four patients and significant oxygen desaturation was detected in a further four patients. Comparison of the measured exercise capacity with resting pulmonary function tests showed many cases of discordance in impairment. In conclusion, pulmonary function defects were detected in half of the recovered severe acute respiratory syndrome patients 3 months after hospital discharge, but the impairment was mild in almost all cases. Many patients had reduced exercise capacity that cannot be accounted for by impairment of pulmonary function. This study was supported by a grant from the A*STAR Biomedical Research Council. ER -