TY - JOUR T1 - 动态充气过度和耐受性间歇运动在晚期COPD JF - 欧洲呼吸杂志JO - EUR呼吸杂志SP - 385 LP - 390 DO - 10.1183 / 09031936.04.00128903 VL - 24 - 3 AU - Vogiatzis，一，非盟 - 咖啡山，S. AU - Kastanakis，E. AU - Georgiadou，O. AU - Papazahou，O. AU - 鲁索斯篇。Y1 - 2004/09/01 UR - //www.qdcxjkg.com/content/24/3/385.abstract N2 - 动态恶性通货膨胀（DH）重要的有助于患者恒定负荷运动（CLE）的限制慢性阻塞性肺疾病（COPD）。然而，其在间歇运动（IE）的限制作用有待探讨。在吸气容量（IC）的变化（Δ）进行测定，以反映DH在27名COPD患者（用力呼气量在一秒平均值±SEM％预计：40±3）的变化在症状限制性CLE测试的末80% of peak work capacity (WRmax) and an IE test at 100% WRmax (30 s of work, alternated with 30 s of unloaded pedalling). At the limit of tolerance in both IE and CLE, patients exhibited similar DH (ΔIC: 0.39±0.05 L and 0.45±0.05 L, respectively). However, exercise endurance time (tend) for IE (32.7±3.0 min) was significantly greater than for CLE (10.3±1.6 min). The IE tend correlated with resting IC, expressed as % pred normal. At 30 and 90% of total IE tend, ΔIC (0.43±0.06 and 0.39±0.05 L, respectively) and minute ventilation (31.1±1.6 and 32.7±2.2 L·min−1, respectively) were not significantly different. Resting hyperinflation helps to explain the limitation of interval exercise. Implementation of interval exercise for rehabilitation should provide important clinical benefits because it prolongs exercise endurance time and allows sustaining higher stable ventilation. This work was supported in part by theEuropean Community. Project title: Computer Aided Rehabilitation of Respiratory Disabilities (CARED) FP5 (contract no. QLG5-CT-2002-0893). ER -