TY - T1的职业性哮喘新雇用工人密集型猪监禁设施JF -欧洲呼吸杂志》乔欧元和J SP - 698 LP - 702 - 10.1183 / 09031936.04.00112102六世- 24 - 4盟多J.A. AU -劳森,J.A. AU - Kirychuk,非盟……- Cormier y盟——Biem J . AU - KoehnckeN. Y1 - 2004/10/01 UR - //www.qdcxjkg.com/content/24/4/698.abstract N2 -在暴露于密集养猪生产设施的工人和naïve志愿者中描述了呼吸道症状、肺功能下降和支气管反应性增加。通常情况下，这种情况发生在长期受雇的人或以前没有接触过的人，naïve志愿者。目前的作者描述了4例病例，均为女性，她们在开始在集约化养猪生产设施全职工作数周内出现哮喘和咳嗽的急性发作。这些工作人员之前都没有哮喘、过敏或花粉热。所有四名雇员都报告说，在设施停止工作后症状有所改善，随后从接触中撤出。然而，当在呼吸诊所就诊时，病例1和3或继续出现轻度症状，或服用药物，分别在停止工作后4和5个月，通过甲胆碱刺激试验测量，气道反应继续处于临界状态。病例2停止工作后症状持续≥3个月。然而，只有病例1在呼吸道门诊反复就诊。一名工人参加了重新入职试验，在入职一小时内出现严重咳嗽和胸闷，之后试验不得不终止。 Provocative concentration causing a 20% fall in forced expiratory volume in one second (PC20) measured 5 h later was lower than pre-trial PC20. No acute exposure event was recorded in the workers prior to the onset of symptoms. To the current authors' knowledge, this is the first report of occupational asthma occurring in newly employed full-time intensive swine production workers after a short-term exposure and should raise awareness that previously unexposed workers may be at risk of developing what would appear to be long-term asthma after relatively short-term exposure. ER -