ty -jour t1-对实验动物的过敏父母儿童的实验动物职业暴露于小鼠，大鼠和仓鼠JF-欧洲呼吸杂志Szulc，B au -Gorski，P Y1-1999/08/01 Ur- http：//www.qdcxjkg.com/content/14/2/352.abstract N2-敏感到实验室动物（LA）的敏感性很高实验室工人。尚不清楚LA过敏原的运输是否可以成为实验室环境以外受试者敏化的危险因素。该研究的目的是调查父母曾经和没有职业暴露于洛杉矶的孩子中对洛杉矶的敏感性的普遍性。第一组由50名儿童（12.3岁+/- 4.3岁）组成，他们的父母在职业上暴露于小鼠，大鼠和仓鼠。第二组由40名儿童（年龄（平均+/- SD）10.8 +/- 3.0年）组成，他们的父母没有在洛杉矶职业。从研究中消除了在家中有洛杉矶的孩子。所有儿童都对问卷进行了回答，进行了肺活量测定法，并通过使用常见的过敏原和刺测测试对小鼠，仓鼠和大鼠的头发提取物进行了测试。还估计了总免疫球蛋白（Ig）E水平和针对LA的特异性IgE的存在。 Children of parents occupationally exposed to LA presented significantly more positive skin prick tests against allergens from the hair of laboratory animals compared to children of nonexposed parents. Five children from the first group were also found to have specific IgE against LA, with three of these five children complaining of rhinitis and cough while visiting their parents' workplace. It is concluded that the observed increased sensitization to laboratory animals among children of occupationally exposed parents could be the result of poor hygienic conditions at their parents' workplace. Hence, parents' job seems to be an additional risk factor of sensitization and should be taken into consideration when recording an allergic history. ER -