TY - T1的过敏实验动物在孩子的父母职业性暴露小鼠,大鼠和仓鼠JF -欧洲呼吸杂志》乔和J SP - 352 LP - 356欧元六世- 14 - 2非盟Krakowiak盟——Szulc B非盟- Gorski,N2 -实验室工作人员对实验动物(LA)敏感的患病率很高。目前尚不清楚洛杉矶变应原的运输是否可能是实验室环境外受试者致敏的危险因素。本研究的目的是调查父母在职业上暴露于洛杉矶和没有暴露于洛杉矶的儿童对洛杉矶敏感的患病率。第一组包括50名儿童(年龄12.3+/-4.3岁)，他们的父母职业暴露于老鼠、大鼠和仓鼠。第二组由40名儿童组成(年龄(平均+/-SD) 10.8+/-3.0岁)，他们的父母没有职业暴露于洛杉矶。家中患有洛杉矶病的儿童被排除在研究之外。所有儿童都回答了一份问卷，接受了肺活量测定，还接受了使用常见过敏原的皮肤点刺试验和小鼠、仓鼠和大鼠毛发提取物的点刺试验。还估计了总免疫球蛋白(Ig)E水平和抗LA特异性IgE的存在。父母职业性接触洛杉矶的儿童对实验室动物毛发过敏源的皮肤点刺试验明显比父母无接触的儿童阳性。 Five children from the first group were also found to have specific IgE against LA, with three of these five children complaining of rhinitis and cough while visiting their parents' workplace. It is concluded that the observed increased sensitization to laboratory animals among children of occupationally exposed parents could be the result of poor hygienic conditions at their parents' workplace. Hence, parents' job seems to be an additional risk factor of sensitization and should be taken into consideration when recording an allergic history. ER -