TY -的T1 -唤醒gastro-oesophageal回流和睡眠呼吸暂停患者JF -欧洲呼吸杂志》乔和J SP - 1266 LP - 1270欧元六世- 14 - 6盟Penzel T非盟-贝克尔,高频非盟-勃兰登堡,U AU - Labunski, T非盟- Pankow W非盟-彼得,JH Y1 - 1999/12/01 UR - //www.qdcxjkg.com/content/14/6/1266.abstract N2 -夜间gastro-oesophageal回流一直在观察阻塞性睡眠呼吸暂停(OSA)患者。胸内压-在呼吸暂停和兴奋已经提出作为底层机制。为了评估这一假说,兴奋的巧合和序列在时间,呼吸暂停和回流事件进行分析。十五阻塞性睡眠呼吸暂停综合症患者或严重打鼾的手段研究了标准polysomnograpy平行记录24小时食管博士回流事件在白天出现在所有患者中,5人反胃的症状。在三种和其他五个病人,69夜间回流事件被发现。在68年的事件,唤起与反流事件被发现。只有一个回流没有唤起被发现(睡眠阶段2)。17事件发生在入睡后清醒。The percentage of time with a pH of <4 during wakefulness after sleep onset was significantly higher than the percentage of time with a pH of <4 during total sleep time (p<0.05). In 37 of the 52 reflux events which occurred during sleep, either an apnoea or a hypopnoea was found prior to the event. The investigation of sequence in time did not prove a causal relation between respiratory events and reflux events. The results indicate that gastro-oesophageal reflux and obstructive sleep apnoea are two separate disorders, which both have a high prevalence in obese patients. ER -