TY -的T1 -定量texture-based分析胸部CT肺实质功能:与光密度指数和短期效果改变吸烟习惯摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.02618 -2021欧元六世- 60 - 4 SP - 2102618 AU - Chiara罗梅伊非盟-罗伯托Castellana盟-芭芭拉孔蒂盟Pietro Bemi AU -亚历山德罗Taliani盟-弗朗西斯科·Pistelli盟-罗纳德·a·Karwoski AU -劳拉Carrozzi盟Annalisa De Liperi AU -布莱恩Bartholmai Y1 - 2022/10/01 UR - //www.qdcxjkg.com/content/60/4/2102618.abstract N2 -目的探讨光密度之间的相关性和计算机辅助肺信息学病理学评价和评级(卡钳)肺气肿的派生指数及其变化在短期内期组患者不同的吸烟习惯。方法回顾性研究包括284名被试从ITALUNG试验(198名男性和86名女性;平均±标准差60±4岁)接受低剂量胸部计算机断层扫描在基线和2年随访。受试者分成四组(restarters持续吸烟,戒烟者和前吸烟者)根据他们的吸烟习惯在基线和随访。光密度和纹理分析,使用卡尺软件。CALIPER-derived之间进行了相关分析低密度区域(LAAs)和密度测量指标,包括15百分位全部肺衰减直方图(Perc15)和相对密度的地区≤950−胡锦涛(RA950)。光密度指数和LAAs在基线评估评估纵向变化和对比组用不同的吸烟习惯。进一步分析每肺区进行实质的变化。结果LAAs强烈与Perc15 (rs = 0.81;术;0.001)和RA950 (rs = 0.905;术中,0.001)。在基线,群烟民显示Perc15更高,RA950低,LAAs(特别是轻微LAAs子类)比群烟(术中,0.001)。 At 2-year follow-up, densitometric indices and LAAs increased in persistent smokers, former smokers and quitters (p<0.05). The progression was larger and statistically more significant in quitters (p<0.001).Conclusion CALIPER texture analysis provides an objective measure comparable to traditional density/histogram features to assess the lung parenchymal changes in relation to different smoking habits.CALIPER texture analysis provides an objective measure comparable to traditional density/histogram features to assess the lung parenchymal changes in relation to different smoking habits https://bit.ly/3tiIF9a ER -