RT期刊文章SR电子T1与固定的气流阻塞哮喘的患病率和特征:欧洲CADSET multi-cohort协作摩根富林明欧洲呼吸杂志乔和J FD欧元欧洲呼吸学会SP PA3515做10.1183/13993003.国会- 2021。188bet官网地址PA3515 VO 58 5 65 A1 Ahmed Edris A1 Judith Garcia-Aymerich A1罗莎·凡尔服饰A1 Howraman Meteran A1托本Sigsgaard A1彼得改变A1老人Vogelmeier A1 Nuria Olvera A1 Nazanin Zounemat-Kermani A1乙烯树脂Agusti A1加文·唐纳森A1门当户对Wedzicha A1家伙Brusselle A1海伦娜后方A1 h . Marike Boezen A1 Judith Vonk A1伊恩·阿德科克A1 Maarten Van Den Berge A1 Lahousse年2021 UL //www.qdcxjkg.com/content/58/suppl_65/PA3515.abstract AB哮喘在于固定气流阻塞(AFO)是一个重要的替代次表型包括哮喘和慢性阻塞性肺病的特性。我们旨在确定AFO的患病率和并发症的病人在一个大型multi-cohort样本。病人至少50岁与肺功能数据来自欧洲九个组(69866人),包括以人群为基础的研究,COPD-based研究和asthma-based研究。AFO是定义为一个记录医生的诊断哮喘和FEV1 / FVC的比< 0.7。灵敏度分析使用正常的下限(LLN)截止相反比较流行。AFO患者并发症患病率之间的比较,哮喘没有固定的气流阻塞,慢性阻塞性肺病(FEV1 / FVC的比< 0.7没有哮喘)。AFO的患病率(n = 2378)以人群为基础的群组之间的不同(2.0%,n = 1299/63504), COPD-based组(15.9%,n = 857/5,402)和asthma-based组(23.1%,n = 222/960)。LLN-based定义显示低AFO一般和哮喘的人群的流行率高(1.4%和15.7%),但在COPD吸烟人口患病率(20.6%)。而高血压是最常见的疾病在所有3个条件,AFO患者更有可能被诊断为抑郁症,骨质疏松症,冠心病和asthma-alone或COPD-alone相比胃食管反流。AFO在一般人群患病率从2.0%到23.1%的哮喘。 The LLN-based definition seems to detect more patients suffering from AFO in populations with substantial smoking history. AFO patients have frequent comorbidities which may underlie their worse health outcomes.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3515.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).