ty -jour t1-哮喘和固定气流阻塞JF的较老的非吸烟者的动态依从性和电抗性 - 欧洲呼吸杂志Timothy au -Chapman,David G. Au -Rutting,Sandra au -Thamrin,Cindy au -King,Gregory G. Au -Tonga,Katrina O./Content/58/2/2004400.Abstract N2-在哮喘中,气道和肺组织的异常机械性能导致气道变窄和通风分布的变化[1]。通风分布取决于时间常数的变化[2],即单个肺单位的电阻和静态依从性的乘积。在健康的肺中,通风分布是异质的,但在包括哮喘在内的气道疾病中,通风分布更高[3]。这是因为由于电阻和符合性的变化,时间常数在疾病中通常更加异质[3,4]。在动态条件下测量的肺合顺顺作,例如在呼吸过程中(动态依从性或CDYN)对时间常数的这些异质性敏感。CDYN相对于静态依从性(CSTAT)的降低,随着通气异质性的增加[2,3,5],由于通风从肺部单位转移到较长的肺部单元向较短的时间常数[6]。因此,CDYN是在潮汐呼吸条件下与通风异质性有关的肺功能的量度,它补充了肺活量测定法。 However, Cdyn is not used clinically because it requires invasive oesophageal pressure measurements.In older non-smokers with asthma and fixed airflow obstruction, X5 measured by oscillometry reflects dynamic rather than static compliance. Distinguishing between dynamic and static compliance is important as they are due to different factors. https://bit.ly/3th0uEr ER -