RT Journal第SR电子T1功能呼吸成像为支气管扩张性无疑JF的长期呼吸道后遗症提供了新的见解JF欧洲呼吸道期刊Jo EUR Respir J FD欧洲呼吸协会SP 2002110 Do 10.1183 / 13993003.02110-2020 VO 57是6 A1 Vanhaverbeke,Kristien188bet官网地址A1 SLAATS,MONIQUE A1 AL-NEJAR,MOHAMMED A1 EVERAARS,NIEK A1 SPINHOVEN,MAARTEN A1 EL ADDOURI,HAROUN A1 LAUWERS,ELINE A1 VAA EYCK,ANNER A1 DE冬季,BENEDICTE Y. A1 VAN HOLENBEECK,KIM A1 VEDooy,Jozef A1 Mahieu,Ludo A1 Mignot,Benjamin A1 De Backer,Jan A1 Mulder,Antonius A1 Verhulst,Stijn Yr 2021 UL //www.qdcxjkg.com/content/57/6/2002110.Abstract Ab理论支气管尿胆怯发育不良(BPD)是早产的常见并发症。肺功能和成像经典用于评估BPD。功能性呼吸成像(FRI)结合了气道及其脉管系统的结构和功能评估。我们的目标是使用FRI评估BPD,并通过临床介绍将这些发现与这些结果相关联。方法包括37个具有早产史(22例BPD病例和15个早料控制)的青少年。研究方案包括详细的历史,肺功能测试和计算断层扫描(CT)(以完全肺容量(TLC)和功能性残留能力(FRC))。CT图像也使用Aukland评分系统进行评估。结果BPD患者在1 s中具有较低的强制呼气量,以强制生气能力比(P = 0.02)和扩散能力受损(P = 0.02)。两组之间的Aukland CT得分与不同的分数不同。 FRI analysis showed higher lobar volumes in BPD patients at FRC (p<0.01), but not at TLC. Airway resistance was significantly higher in the BPD group, especially in the distal airways. Additionally, FRI showed more air trapping in BPD patients, in contrast to findings on conventional CT images.Conclusion This study is the first to use FRI in research for BPD. FRI analysis showed higher lobar volumes in BPD patients, indicating air trapping and reduced inspiratory capacity. In contrast to Aukland CT scores, FRI showed more air trapping in the BPD group, suggesting that FRI might be a more sensitive detection method. Importantly, we also showed increased distal airway resistance in BPD patients. By combining structural and functional assessment, FRI may help to better understand the long-term sequelae of BPD.This study assesses respiratory outcomes in adolescents born preterm. BPD patients had impaired lung function. FRI showed higher distal airway resistances and more air trapping in the BPD group and seems to be a more sensitive emerging imaging technique. https://bit.ly/2KzZytp