TY - T1的呼吸功能成像提供了新颖的见解的长期呼吸后遗症支气管肺的发育不良JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02110 -2020欧元六世- 57 - 6 SP - 2002110 AU Vanhaverbeke Kristien盟——Slaats Monique AU - Al-Nejar,默罕默德盟——EveraarsNiek盟——Snoeckx Annemiek盟——Spinhoven Maarten AU - El Addouli哈盟——Lauwers Eline盟——范艾克Annelies AU - De冬天,新兴市场y . AU - Van Hoorenbeeck金盟- De Dooy约瑟夫盟——Mahieu骰子游戏非盟等,本杰明AU -德支持者,1月盟——穆德,托尼斯盟——Verhulst支气管肺发育不良(BPD)是一种常见的早产并发症。肺功能和影像学是评估BPD的经典方法。功能呼吸成像(FRI)结合了气道及其血管系统的结构和功能评估。我们的目的是用FRI评估BPD，并将这些发现与临床表现联系起来。方法纳入37例有早产史的青少年(22例BPD和15例早产儿对照)。研究方案包括详细的病史、肺功能测试和使用FRI的计算机断层扫描(CT)(总肺容量(TLC)和功能剩余肺容量(FRC))，并使用奥克兰评分系统评估CT图像。结果BPD患者1 s用力呼气量与用力肺活量比值较低(p=0.02)，弥散能力受损(p=0.02)。两组间奥克兰CT评分无差异。FRI分析显示，在FRC时BPD患者的大叶体积较高(p<0.01)，而在TLC时没有。 Airway resistance was significantly higher in the BPD group, especially in the distal airways. Additionally, FRI showed more air trapping in BPD patients, in contrast to findings on conventional CT images.Conclusion This study is the first to use FRI in research for BPD. FRI analysis showed higher lobar volumes in BPD patients, indicating air trapping and reduced inspiratory capacity. In contrast to Aukland CT scores, FRI showed more air trapping in the BPD group, suggesting that FRI might be a more sensitive detection method. Importantly, we also showed increased distal airway resistance in BPD patients. By combining structural and functional assessment, FRI may help to better understand the long-term sequelae of BPD.This study assesses respiratory outcomes in adolescents born preterm. BPD patients had impaired lung function. FRI showed higher distal airway resistances and more air trapping in the BPD group and seems to be a more sensitive emerging imaging technique. https://bit.ly/2KzZytp ER -